A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection[1][2].
Molecular Weight:
621.73
Purity:
99.89
CAS Number:
[869748-10-7]
Formula:
C34H39N9O3
Target:
Src
Application Notes:
MCE Product type: Reference compound
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