NBI-31772 is a non-selective IGFBP inhibitor (Ki=47 nM). NBI-31772 has neuroprotective effects and reduces infarct volume during cerebral ischemia. NBI-31772 can also restore or enhance proteoglycan synthesis in osteoarticular chondrocytes. In addition, NBI-31772 also increases the effect of IGF3 on zebrafish oocyte maturation[1][2][3][4].
Molecular Weight:
341.27
Purity:
98.88
CAS Number:
[374620-70-9]
Formula:
C17H11NO7
Target:
IGF-1R
Application Notes:
MCE Product type: Reference compound
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