NBI-31772 hydrate is a potent inhibitor of interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). NBI-31772 hydrate is also a nonpeptide ligand that releases bioactive IGF-I from the IGF-I/IGFBP-3 complex (Kis=1-24 nM for all six human subtypes). Anxiolytic and antidepressant-like effects[1][2][3].
Molecular Weight:
372.82
Purity:
99.42
Formula:
C17H11NO7.7/4H2O
Target:
IGF-1R
Application Notes:
MCE Product type: Reference compound
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