NB-216 is an orally active and brain-penetrant BACE-1 inhibitor (IC50 = 17 nM). NB-216 has a strong inhibitory effect on cathepsin D (IC50 = 1 nM) and cathepsin E (IC50 = 0.4 nM). NB-216 can be used for the study of Alzheimers disease[1].
Molecular Weight:
571.75
CAS Number:
[943924-04-7]
Formula:
C35H45N3O4
Target:
Beta-secretase,Cathepsin
Application Notes:
MCE Product type: Reference compound1
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