LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist. LM11A-31 dihydrochloride is an amino acid derivative with high blood-brain barrier permeability and blocks p75-mediated cell death. LM11A-31 dihydrochloride reverses cholinergic neurite dystrophy in Alzheimers disease mouse models with mid- to late-stage disease progression[1][2].
Molecular Weight:
316.27
Purity:
99.93
CAS Number:
[1243259-19-9]
Formula:
C12H27Cl2N3O2
Target:
Neurotensin Receptor
Application Notes:
MCE Product type: Reference compound1
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