Pozanicline dihydrochloride (ABT-089 dihydrochloride) is an orally bioavailable nicotinic acetylcholine receptor (nAChR) agonist with a Ki of 16.7 nM for binding to [3H]cytisine sites[1]. Pozanicline is an alpha4beta2-selective nAChR agonist, which binds to rat brain alpha4beta2 nAChR with a Ki of 17 nM while binding to alpha7 nAChR is insignificant[2].
Molecular Weight:
265.18
Purity:
99.06
CAS Number:
[161416-61-1]
Formula:
C11H18Cl2N2O
Target:
nAChR
Application Notes:
MCE Product type: Reference compound1
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