PK-THPP is a potent and brain-penetrant TWIK-related acid-sensitive K+ ion channel (K2P9.1 or TASK-3) blocker with IC50s of 35 nM and 300 nM for TASK-3 and TASK-1, respectively. PK-THPP shows no or less activity against other K+ channels. PK-THPP is an effective breathing stimulant and can be used for the study of breathing disorders[1][2].
Molecular Weight:
468.59
Purity:
99
CAS Number:
[1332454-07-5]
Formula:
C29H32N4O2
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound1
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