ML 297 (VU 0456810) is a potent and selective GIRK1/2 activator, with an EC50 of 0.16 µM. ML 297 can cross the blood-brain barrier with brain-to-plasma ratio of 0.2 in mice model (i.p.). ML 297 is potential for the treatment of epilepsy[1][2].
Molecular Weight:
328.32
Purity:
99.14
CAS Number:
[1443246-62-5]
Formula:
C17H14F2N4O
Target:
Potassium Channel
Application Notes:
MCE Product type: Reference compound
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