5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation[1].
Molecular Weight:
312.35
Purity:
95
CAS Number:
[827001-82-1]
Formula:
C16H12N2O3S
Target:
CRAC Channel
Application Notes:
MCE Product type: Reference compound1
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