BMS-566419 is an orally active IMPDH inhibitor with an IC50 of 91 nM against human IMPDH I and 68 nM against human IMPDH II. BMS-566419 exerts anti-heart transplant rejection and anti-renal fibrosis effects, and inhibits the expression of MCP-1, TGF-beta1 as well as antibody production. BMS-566419 can be used in research on renal fibrosis and organ transplantation[1][2].
Molecular Weight:
487.57
Purity:
99.68
CAS Number:
[566161-24-8]
Formula:
C28H30FN5O2
Target:
IMPDH
Application Notes:
MCE Product type: Reference compound
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