CIM0216, a synthetic TRPM3 ligand, acts as a potent and selective agonist of TRPM3. CIM0216 exhibits selectivity for TRPM3 over TRPM1, TRPM2 and TRPM4-8. CIM0216 acts in a TRPM3-dependent manner to induce pain and evoke neuropeptide release from sensory nerve terminals in vitro. CIM0216 is a powerful tool for studies of the physiological functions of TRPM3, and can be used for neurogenic inflammation research[1].
Molecular Weight:
347.41
Purity:
99.94
CAS Number:
[1031496-06-6]
Formula:
C21H21N3O2
Target:
TRP Channel
Application Notes:
MCE Product type: Reference compound
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