Ogerin, a chemical probe, is a selective GPR68 positive aliasing modulator (PAM) (pEC50=6.83) with a moderate antagonistic effect on A2A (Ki=220 nM). Ogerin inhibits the fear conditioning reflex in mice and also inhibits TGF-beta-induced myofibroblast differentiation of fibroblasts from multiple organ systems. Ogerin can be used in the studies of fibrotic diseases and neurological disorders[1][2].
Molecular Weight:
307.35
Purity:
99.94
CAS Number:
[1309198-71-7]
Formula:
C17H17N5O
Target:
GPR68
Application Notes:
MCE Product type: Reference compound
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