BMS-599626 (dihydrochloride), CAS [[1781932-33-9]] Preis auf Anfrage

Product Overview

• Article Name: BMS-599626 (dihydrochloride), CAS [[1781932-33-9]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-110333
• Supplier Catalog Number: HY-110333
• Alternative Catalog Number: MCE-HY-110333-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

BMS-599626 dihydrochloride is a small molecule pan-HER (human epidermal growth factor receptor) kinase inhibitor. BMS-599626 dihydrochloride primarily targets HER1 (IC50=20 nmol/L) and HER2 (IC50=30 nmol/L) kinase activity in the HER family. BMS-599626 inhibits the kinase activity of HER1 and HER2 by competing with their ATP-binding sites, and can inhibit the downstream signaling pathway by blocking the heterodimer formation of HER1 and HER2. BMS-599626 dihydrochloride can be used to study the antitumor effects of multiple HER1 or HER2 overexpressed tumor models[1].

Product Properties

• Molecular Weight: 603.48
• CAS Number: [1781932-33-9]
• Formula: C27H29Cl2FN8O3
• Target: EGFR

Application Notes

• Application Notes: MCE Product type: Reference compound1