BS-181 (dihydrochloride), CAS [[1883548-83-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-110368
Supplier Catalog Number:
HY-110368
Alternative Catalog Number:
MCE-HY-110368-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
BS-181 dihydrochloride is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880 nM, 3000 nM and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 dihydrochloride inhibits a panel of cancer cells growth (IC50=11.5 µM-37.3 µM) and induces cell apoptosis. BS-181 dihydrochloride has the potential for the research of cancer therapy[1][2].
Molecular Weight:
453.45
CAS Number:
[1883548-83-1]
Formula:
C22H34Cl2N6
Target:
CDK
Application Notes:
MCE Product type: Reference compound
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