PF-3052334 is an orally active, hepatically selective HMG-CoA reductase inhibitor with an IC50 of 1.9 nM. PF-3052334 inhibits cholesterol synthesis, with IC50 values of 0.9 and 730 nM in hepatocytes and muscle cells, respectively. PF-3052334 can be used to study hypercholesterolemia[1].
Molecular Weight:
533.57
CAS Number:
[887702-61-6]
Formula:
C28H33FN3NaO5
Target:
HMG-CoA Reductase (HMGCR)
Application Notes:
MCE Product type: Reference compound
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