DPC423 is a selective and orally active factor Xa inhibitor with a Kis of 0.15 (human) and 0.3 (rabbit) nM. DPC423 exhibits Kis of 60, 61 and 6000 nM against human trypsin, plasma kallikrein and thrombin. DPC423 blocks the formation of prothrombinase complex, reduces thrombin production, inhibits fibrin formation and platelet activation. DPC423 can be used for the study of anticoagulation of arterial thrombosis[1][2].
Molecular Weight:
568.97
CAS Number:
[292135-59-2]
Formula:
C25H21ClF4N4O3S
Target:
Factor Xa,Kallikrein,Ser/Thr Protease,Thrombin
Application Notes:
MCE Product type: Reference compound1
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