GSK461364 analogue 1, CAS [[929095-23-8]] Preis auf Anfrage

Product Overview

• Article Name: GSK461364 analogue 1, CAS [[929095-23-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-111090
• Supplier Catalog Number: HY-111090
• Alternative Catalog Number: MCE-HY-111090-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

GSK461364 analogue 1 is a thiophene-based PLK1 inhibitor with a PLK1 IC50 of 2 nM and a PLK3 IC50 of 630 nM. GSK461364 analogue 1 also acts as an inhibitor of Nek2 kinase (IC50: 21 nM). GSK461364 analogue 1 has a solubility of 190 µM in pH 7.4 PBS and a human plasma protein binding rate of 91.5%. GSK461364 analogue 1 can be used in studies related to colon cancer, lung cancer, breast cancer and ovarian cancer[1].

Product Properties

• Molecular Weight: 511.04
• CAS Number: [929095-23-8]
• Formula: C26H27ClN4O3S
• Target: NEKs,Polo-like Kinase (PLK)

Application Notes

• Application Notes: MCE Product type: Reference compound