ONO-2952 is a potent, selective and orally active translocator protein 18 kDa (TSPO) antagonist with Ki of 0.33-9.30 nM for rat and human TSPO. ONO-2952 is more selective for TSPO than other receptors, transporters, ion channels and enzymes. ONO-2952 exerts its anti-stress effects through inhibition of excessive activation of noradrenergic system in the brain without the amnesic effect. ONO-2952 has the potential for irritable bowel syndrome treatment[1][2].
Molecular Weight:
398.86
Purity:
99.51
CAS Number:
[895169-20-7]
Formula:
C22H20ClFN2O2
Target:
Adrenergic Receptor
Application Notes:
MCE Product type: Reference compound
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