AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 µM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction[1].
Molecular Weight:
467.87
Purity:
99.23
CAS Number:
[878983-38-1]
Formula:
C22H21ClF3N3O3
Target:
Mitochondrial Metabolism,VDAC
Application Notes:
MCE Product type: Reference compound
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