JGB1741, CAS [[1256375-38-8]]

Product Overview

• Article Name: JGB1741, CAS [[1256375-38-8]]
• Biozol Catalog Number: MCE-HY-111329
• Supplier Catalog Number: HY-111329
• Alternative Catalog Number: MCE-HY-111329-10MG,MCE-HY-111329-1MG,MCE-HY-111329-25MG,MCE-HY-111329-50MG,MCE-HY-111329-5MG,MCE-HY-111329-100MG
• Manufacturer: MedchemExpress
• Category: Biochemikalien
• Alternative Names: ILS-JGB-1741

Product Description

JGB1741 (ILS-JGB-1741) is a potent and specific SIRT1 activity inhibitor with an IC50 of ~15 µM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 µM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research[1].

Product Properties

• Molecular Weight: 440.56
• Purity: 99.36
• CAS Number: [1256375-38-8]
• Formula: C27H24N2O2S
• Target: Apoptosis,Sirtuin

Application Notes

• Application Notes: Reference compound