EPAC 5376753, a 2-Thiobarbituric acid (HY-77962) derivative, is a selective and allosteric Epac inhibitor. EPAC 5376753 inhibits Epac1 with an IC50 of 4 µM in Swiss 3T3 cells. EPAC 5376753 does not inhibit PKA and adenylyl cyclases[1].
Molecular Weight:
367.21
Purity:
98.10
CAS Number:
[302826-61-5]
Formula:
C15H8Cl2N2O3S
Target:
Ras
Application Notes:
MCE Product type: Reference compound
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