BSc5371 is a potent and irreversible FLT3 inhibitor, with Kds of 1.3, 0.83, 1.5, 5.8 and 2.3 nM for mutant FLT3(D835H), FLT3(ITD, D835V), FLT3(ITD, F691L), FLT3-ITD and wild type FLT3wt, respectively. BSc5371 is cytotoxic to FLT3-dependent cell lines[1].
Molecular Weight:
485.60
CAS Number:
[2286419-03-0]
Formula:
C24H31N5O4S
Target:
FLT3
Application Notes:
MCE Product type: Reference compound
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