BI-3663 is a highly selective PTK2/FAK PROTAC (DC50=30 nM), with Cereblon ligands to hijack E3 ligases for PTK2 degradation. BI-3663 inhibits PTK2 with an IC50 of 18 nM. BI-3663 is a PROTAC that composes of BI-4464 (HY-124625) linked to Pomalidomide (HY-10984) with a linker[1]. Anti-cancer activity[1].
Molecular Weight:
917.84
Purity:
99.84
CAS Number:
[2341740-84-7]
Formula:
C44H42F3N7O12
Target:
FAK,PROTACs
Application Notes:
MCE Product type: Reference compound
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