Bragsin2 is a potent, selective and noncompetitive nucleotide exchange factor BRAG2 inhibitor, with an IC50 of 3 µM. Bragsin2 binds at the interface between the PH domain of BRAG2 and the lipid bilayer, leads BRAG2 unable to activate lipidated Arf GTPase. Bragsin2 affects breast cancer stem cells[1].
Molecular Weight:
289.16
Purity:
99.85
CAS Number:
[342795-08-8]
Formula:
C11H6F3NO5
Target:
MDM-2/p53,Ras
Application Notes:
MCE Product type: Reference compound1
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