FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC50, 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo[1].
Molecular Weight:
409.41
Purity:
99.39
CAS Number:
[1630808-89-7]
Formula:
C22H20FN3O4
Target:
Fatty Acid Synthase (FASN)
Application Notes:
MCE Product type: Reference compound1
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