3-Azido-3-deoxy-5-methylcytidine (CS-92) is a potent xenotropic murine leukemia-related retrovirus (XMRV) inhibitor with a CC50 of 43.5 µM in MCF-7 cells. 3-Azido-3-deoxy-5-methylcytidine also inhibits HIV-1 reverse transcriptase with an EC50 of 0.06 µM in peripheral blood mononuclear (PBM) cells[1]. 3-Azido-3-deoxy-5-methylcytidine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Molecular Weight:
282.26
Purity:
99.90
CAS Number:
[1282040-14-5]
Formula:
C10H14N6O4
Target:
HIV,Reverse Transcriptase
Application Notes:
MCE Product type: Reference compound
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