WDR5-IN-4 TFA (Compound C6) is an inhibitor of the WIN site of chromatin-associated WD repeat-containing protein 5 (WDR5), with a Kd of 0.1 nM. WDR5-IN-4 TFA displaces WDR5 from chromatin and decreases the expression of associated genes, causing translational inhibition, nucleolar stress. Anti-cancer activity[1].
Molecular Weight:
612.40
Purity:
98.04
CAS Number:
[2749300-35-2]
Formula:
C27H23Cl2F4N5O3
Target:
Apoptosis,WDR5
Application Notes:
MCE Product type: Reference compound
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