8-Mercaptoguanosine is an immunoadjuvant that affects the in vivo antibody response to the T-cell-independent antigen TNP-Ficoll. 8-Mercaptoguanosine enhances IgG1, IgG2, and IgG3 antibody responses, but has no effect on IgM antibody responses. 8-Mercaptoguanosine also enhances antibody responses to very weak antigens such as pneumococcal polysaccharide and restores antibody responses in immunodeficient xid mice that are non-reactive to TNP-Ficoll[1][2].
Molecular Weight:
315.31
Purity:
98
CAS Number:
[26001-38-7]
Formula:
C10H13N5O5S
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Reference compound
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