SCYX-6759 is an orally active, blood-brain barrier permeable anti-T. brucei agent. SCYX-6759 inhibits cytochrome P450 (IC50s: 30.3, 30.6, 47.4 µM for 2D6, 2C9, 2C19, respectively.) SCYX-6759 exhibits potent activity against T. b. brucei 427, T. b. rhodesiense STIB900, and T. b. gambiense STIB930, with IC50s of 0.07, 0.038 and 0.030 µg/mL, respectively[1].
Molecular Weight:
339.05
CAS Number:
[1222509-12-7]
Formula:
C15H10BF4NO3
Target:
Cytochrome P450,Parasite
Application Notes:
MCE Product type: Reference compound
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