BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7[1].
Molecular Weight:
442.43
Purity:
99.91
CAS Number:
[2361241-23-6]
Formula:
C23H21F3N4O2
Target:
TRP Channel
Application Notes:
Reference compound
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