5-Iodo-indirubin-3-monoxime is a potent GSK-3beta, CDK5/P25 and CDK1/cyclin B inhibitor, competing with ATP for binding to the catalytic site of the kinase, with IC50s of 9, 20 and 25 nM, respectively[1].
Molecular Weight:
403.17
Purity:
99.50
CAS Number:
[331467-03-9]
Formula:
C16H10IN3O2
Target:
CDK,GSK-3
Application Notes:
Reference compound
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