BAY-707, a chemical probe, is a substrate-competitive, highly potent and selective inhibitor of MTH1(NUDT1) with an IC50 of 2.3 nM. BAY-707 has a good pharmacokinetic (PK) profile to other MTH1 compounds and is well-tolerated in mice, but shows a clear lack of in vitro or in vivo anticancer efficacy[1].
Molecular Weight:
288.34
Purity:
99.64
CAS Number:
[2109805-96-9]
Formula:
C15H20N4O2
Target:
DNA/RNA Synthesis
Application Notes:
MCE Product type: Reference compound1
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