ABBV-744 is a first-in-class, orally active and selective inhibitor of the BDII domain of BET family proteins with IC50 values ranging from 4 to 18 nM for BRD2, BRD3, BRD4 and BRDT. ABBV-744 is primarily metabolized by CYP3A4 with agent-like properties enable the investigation of its antitumor efficacy and tolerability[1].
Molecular Weight:
491.55
Purity:
99.95
CAS Number:
[2138861-99-9]
Formula:
C28H30FN3O4
Target:
Epigenetic Reader Domain,HIV
Application Notes:
MCE Product type: Reference compound
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