GSK180 is a selective, competitive, and potent inhibitor of kynurenine-3-monooxygenase (KMO), a key enzyme of tryptophan metabolism (IC50, ~6 nM), but shows negligible activity against other enzymes on the tryptophan pathway. GSK180 rapidly changes levels of kynurenine pathway metabolites, and acts as a useful tool to probe the therapeutic potential of KMO inhibition[1].
Molecular Weight:
276.07
Purity:
98.34
CAS Number:
[1799725-26-0]
Formula:
C10H7Cl2NO4
Target:
KMO
Application Notes:
MCE Product type: Reference compound
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