Shield-1 (Shld1) is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize proteins tagged with a mutated FKBP12-derived destabilization domain (DD)[1][2][3].
Molecular Weight:
748.90
Purity:
99.73
CAS Number:
[914805-33-7]
Formula:
C42H56N2O10
Target:
FKBP
Application Notes:
MCE Product type: Reference compound
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