Pralsetinib (BLU-667) is a highly potent, selective RET inhibitor. Pralsetinib (BLU-667) inhibits WT RET, RET mutants V804L, V804M, M918T and CCDC6-RET fusion with IC50s of 0.4, 0.3, 0.4, 0.4, and 0.4 nM, respectively[1].
Molecular Weight:
533.60
Purity:
99.98
CAS Number:
[2097132-94-8]
Formula:
C27H32FN9O2
Target:
RET
Application Notes:
Reference compound
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