SU9518 is a tyrosine kinase inhibitor with specific activity against PDGFRalpha. SU9518 can inhibit the development of proliferative vitreoretinopathy (PVR) in fibroblast and Muller cell rabbit models. SU9518 showed effective inhibitory effects in these models without toxic effects. Therefore, SU9518 has the potential to be used to inhibit PVR in humans and other proliferative eye diseases involving fibrosis and gliosis[1].
Molecular Weight:
389.24
CAS Number:
[251356-32-8]
Formula:
C18H17BrN2O3
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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