Scytonemin is a hydrophobic alkaloid pigment that can be isolated from the outer sheath of cyanobacteria. Scytonemin has protective function against short-wave solar ultraviolet (UV) radiation, which can reduce the generation of reactive oxygen species (ROS) and the formation of DNA damage. Scytonemin also has anti-inflammatory and anti-proliferative activities, produces concentration-dependent inhibition (IC50=2.0 µM) of polo-like kinase 1 (PLK1)-mediated cdc25C phosphorylation, and plays an important role in regulating the G2/M transition in the cell cycle. It can be used in the research of cancer, acute inflammation and sunscreen cosmetics[1][2][3][4][5].
Molecular Weight:
544.56
Purity:
99.53
CAS Number:
[152075-98-4]
Formula:
C36H20N2O4
Target:
Apoptosis,Polo-like Kinase (PLK),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
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