TX-1918 is an inhibitor for eukaryotic elongation factor 2 kinase (eEF2-K) and Src kinase with IC50 of 0.44 and 4.4 µM, respectively. TX-1918 exhibits cytotoxicity in cell HepG2 and HCT116, with IC50 of 2.07 and 230 µM, respectively. TX-1918 inhibits the C-terminal domain of HIV-1 CA (CA CTD)(IC50 =3.81 µM), and inhibits the viral replication (IC50 =15.16 µM)[1][2].
Molecular Weight:
228.24
CAS Number:
[503473-32-3]
Formula:
C14H12O3
Target:
HIV,PKA,PKC,Src
Application Notes:
MCE Product type: Reference compound
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