HZX-02-059 is a potent methuosis inducer and dual-target PIKfyve/tubulin inhibitor with anticancer activity. Methuosis mainly disrupts the balance of endocytosis and exocytosis, forming a large number of vesicles and inducing cell death. HZX-02-059 also induces cell vacuolization, promotes apoptosis, downregulates the p53 pathway, inhibits PI3K/AKT phosphorylation, and inhibits c-Myc and NF-kappaB transcription[1][2].
Molecular Weight:
487.48
Purity:
99.40
CAS Number:
[2240205-30-3]
Formula:
C27H20F3N5O
Target:
Others
Application Notes:
Reference compound
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