Tivozanib hydrate (AV-951 hydrate, KRN951 hydrate) is the hydrate form of Tivozanib (HY-10977). Tivozanib hydrate is a selective, orally active inhibitor for vascular endothelial growth factor receptor (VEGFR)-1, 2 3, with IC50s of 30, 6.5 and 15 nM, respectively. Tivozanib hydrate exhibits antitumor efficacy[1].
Molecular Weight:
472.88
Purity:
99
CAS Number:
[682745-40-0]
Formula:
C22H21ClN4O6
Target:
VEGFR
Application Notes:
Reference compound
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