Chk2-IN-1 (compound 1) is a potent and selective inhibitor of checkpoint kinase 2 (Chk2), with IC50s of 13.5 nM and 220.4 nM for Chk2 and Chk1, respectively. Chk2-IN-1 can elicit a strong ataxia telangiectasia mutated (ATM)-dependent Chk2-mediated radioprotection effect[1].
Molecular Weight:
295.30
CAS Number:
[724708-21-8]
Formula:
C15H13N5O2
Target:
Checkpoint Kinase (Chk),Choline Kinase
Application Notes:
MCE Product type: Reference compound
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