ABT-702 (Adenosine Kinase Inhibitor) is a potent, orally active, and selective adenosine kinase (AK) inhibitor with an IC50 of 1.7 nM. ABT-702 shows >1300-fold selectivity for AK over other biological targets, including cyclooxygenases-1 and -2. ABT-702 attenuates inflammation in diabetic retinopathy by increasing free adenosine levels. ABT-702 shows analgesic and anti-inflammatory effects in vivo. ABT-702 can be used for diabetic retinopathy research[1][2][3].
Molecular Weight:
463.33
Purity:
99.61
CAS Number:
[214697-26-4]
Formula:
C22H19BrN6O
Target:
Adenosine Kinase,Adenosine Receptor
Application Notes:
MCE Product type: Reference compound
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