EXEL-0346 is an orally active glucosylceramide synthase (GCS) inhibitor, with an IC50 of 2 nM. EXEL-0346 combined with insulin increases pAkt. EXEL-0346 effectively reduces the levels of Glucosylceramide, Lactosylceramide and GM3. EXEL-0346 improves obesity and diabetes[1].
Molecular Weight:
580.44
CAS Number:
[1239893-96-9]
Formula:
C27H29BrF3N3O3
Target:
Glucosylceramide Synthase (GCS)
Application Notes:
MCE Product type: Reference compound
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