Pradefovir is a good substrate for liver CYP3A4. Pradefovir is converted to 9-(2-phosphonylmethoxyethyl)adenine (PMEA) in human liver microsomes with a Km of 60 µM.
Molecular Weight:
423.79
CAS Number:
[625095-60-5]
Formula:
C17H19ClN5O4P
Target:
Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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