CA-5f is a potent late-stage macroautophagy/autophagy inhibitor via inhibiting autophagosome-lysosome fusion. CA-5f increases LC3B-II (a marker to monitor autophagy) and SQSTM1 protein, and also increases ROS production. Anti-tumor activity[1].
Molecular Weight:
388.46
Purity:
99.14
CAS Number:
[1370032-19-1]
Formula:
C24H24N2O3
Target:
Apoptosis,Atg8/LC3,Autophagy,p62
Application Notes:
MCE Product type: Reference compound
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