CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1].
Molecular Weight:
504.52
Purity:
99.60
CAS Number:
[2437547-04-9]
Formula:
C24H23F3N4O3S
Target:
CCR
Application Notes:
MCE Product type: Reference compound
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