Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis. Sparfosic acid synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines[1][2][3].
Molecular Weight:
255.12
Purity:
99.33
CAS Number:
[51321-79-0]
Formula:
C6H10NO8P
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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