Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis. Sparfosic acid trisodium synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines[1][2][3].
Molecular Weight:
321.06
Purity:
98
CAS Number:
[70962-66-2]
Formula:
C6H7NNa3O8P
Target:
Apoptosis
Application Notes:
MCE Product type: Reference compound
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