DK419 is a potent and orally active Wnt/beta-catenin signaling inhibitor, with an IC50 of 0.19 µM. DK419 reduces protein lelvels of Axin2, beta-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK[1].
Molecular Weight:
407.70
Purity:
99.86
CAS Number:
[2102672-22-8]
Formula:
C16H8ClF6N3O
Target:
CDK,c-Myc,Survivin,Wnt,beta-catenin
Application Notes:
Reference compound
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